I saw a post on Dice Tower News that highlighted a storage solution for Dominion cards. I originally used the box insert with the labels like many folks do, but quickly decided that was rather annoying. I found that storing the cards in 3″ x 4″ ziploc bags works much better. Instead of using the card randomizers and then selecting the cards from the slots in the plastic insert, I simply pick 10 of the ziplocs at random. I still keep each set\expansion in their own boxes as I like to play the sets mostly self-contained. It’s quick, cheap, and works well.